Method of delivering a therapeutic agent to a target capillary bed
June 27, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3474777 3663687 Method for incorporating substances into protein microspheres Cancer treatment method Intracellular temperature measurement Albumin medicament carrier system Intravascularly-administrable, magnetically-localizable biodegradable carrier Physiological preparation containing loaded cells in suspension and a magnetic agent for local concentration thereof in a living body Patent #: 4269826 InventorsAssigneeApplicationNo. 06/163716 filed on 06/27/1980US Classes:600/12, Magnetic element placed within body (e.g., injected, inserted, implanted, etc.)252/62.53, With wax, bitumen, resin, or gum604/308Bandage, pad, shield, or attaching means extendable around body portionExaminersPrimary: Howell, Kyle L.Assistant: Swisher, Nancy A. B. International ClassesA61K 41/00 (20060101)A61K 9/50 (20060101) A61K 51/12 (20060101) G01N 33/543 (20060101) AbstractIntravascularly-administrable, magnetically-localizable biodegradable microspheres containing a therapeutic agent, such as an oncolytic agent, are prepared and administered so that they can be permanently localized in a target capillary bed for release of the therapeutic agent therein. The effects of the therapeutic agent can thereby be relatively confined to the area of the capillary bed. Of particular importance is the administration of oncolytic agents by the method, since this permits the undesirable side effects of the oncolytic agents to be substantially reduced, while at the same time increasing the anti-cancer effectiveness of the drug.Other References
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