U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Sustained release pharmaceutical composition of solid medical material

Patent 4343789 Issued on August 10, 1982. Estimated Expiration Date: Icon_subject July 2, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2149005

2540253

2698822

3297804

3308217

3325362

3374146

3458622

3634584

3670065

More ...

Inventors

Assignee

Application

No. 06/165244 filed on 07/02/1980

US Classes:

514/356, C=O in a C(=O)O group (e.g., nicotinic acid, etc.)424/497, Containing solid synthetic polymers426/33, Isolated triglyceride other than milk derived426/80, Having flow compeller means, e.g., compressor, etc.426/81Tapered gathered closure

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

International Classes

A61K 9/14 (20060101)
A61K 9/16 (20060101)
A61K 31/44 (20060101)

Foreign Application Priority Data

1979-07-05 JP

Abstract

Sustained release pharmaceutical composition of a solid medical material which contains an amorphous solid medical material, polyethylene oxide, and at least one basic substance selected from the group consisting of hydroxypropylmethyl cellulose, hydroxypropyl cellulose, methyl cellulose, polyvinyl pyrrolidone, carboxyvinyl polymer, hydroxypropylmethyl cellulose phthalate, cellulose acetate phthalate, methyl meta-acrylate meta-acrylic acid copolymer, polyvinylacetal diethylaminoacetate, dimethylaminoethyl meta-acrylate meta-acrylic acid copolymer, 2-methyl-5-vinylpyridinemethyl acrylate meta-acrylic acid copolymer, citric acid, urea, succinic acid and amino acid, and may further contain one basic substance selected from the group consisting of a surface active agent, polyethylene glycol, propylene glycol, glycerin, a glycerin fatty acid ester and a vegetable oil (first embodiment): and in the case where the solid medical material is nicardipine, the composition may consist only of the amorphous nicardipine or a salt thereof without the above compound (second embodiment).

Other References

  • Chem. Abstracts 91 #96630h (1979) of Kanebo, Ltd., Jpn. Kokai Tokkyo Koho 79 44,034, Apr. 7, 1979, Coronary vasodilating compositions containing nifedipine
  • Chem. Abstracts 93 #155846z, (1980) of Ohta Pharm., Jpn. Kokai Tokkyo Koho 80 22,631, Feb. 18, 1980, Nifedipine pharmaceuticals for easier absorption
  • Chem. Abstracts 93 #210260f (1980) of Taiyo Yakuhin, Jpn. Kokai Tokkyo Koho 80 47,615, Apr. 4, 1980, Stable solid pharmaceuticals of nifedipine
  • Chem. Abstracts 93 #220596j (1980) of Bayer A/G, Jpn. Kokai Tokkyo Koho 80 64,570, May 15, 1980
  • Chem. Abstracts 93 #150124c (1980) of Bayer A/G, Ger. Offen. 2,847,237, May 14, 1980
  • Chem. Abstracts 83 #209407w (1975) of Ger. Offen. 2,400,819 Jul. 17, 1975, Finely divided preparation of difficultly soluble pharmaceuticals, Kramer R. R. Amor et al
  • Chem. Abstracts 87 #28914w (1977) of Eckert, T. et al. Arch. Pharm. (Weinhelm, Ger.) 1977, 310(2), 116-118, Polymorphic modifications of Nifedipine from supercooled melts
  • Chem. Abstracts 90 #109987m (1979) of Ger. Offen. 2,822,882 Dec. 21, 1978, Kawata et al., Nifedipine solid preparations
  • Chem. Abstracts 91 #112451h (1979) of Jpn. Kokai Tokkyo Koho 79 46,837, Apr. 13, 1979 Kanebo, Ltd., Nifedipine-containing vasodilating compositions with good absorption
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$16.95more info
 
Sign InRegister
Username  
Password   
forgot password?