Novel material for immunological assay of biochemical components and a process for the determination of said components

Patent 4342739 Issued on August 3, 1982. Estimated Expiration Date:

January 8, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

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Inventors

Application

No. 06/110318 filed on 01/08/1980

US Classes:

435/7.9, Assay in which an enzyme present is a label424/1.37, Radionuclide or intended radionuclide in an organic compound424/497, Containing solid synthetic polymers428/402.2, Microcapsule with fluid core (includes liposome)428/402.21, Solid-walled microcapsule from synthetic polymer435/4, MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP435/7.92, Heterogeneous or solid phase assay system (e.g., ELISA, etc.)436/518, INVOLVING AN INSOLUBLE CARRIER FOR IMMOBILIZING IMMUNOCHEMICALS436/823, IMMUNOGENIC CARRIER OR CARRIER PER SE436/829LIPOSOMES (E.G., ENCAPSULATION, ETC.)

Examiners

Primary: Nucker, Christine M.

Attorney, Agent or Firm

Sughrue, Mion, Zinn, Macpeak & Seas

International Classes

G01N 33/545 (20060101)
G01N 33/544 (20060101)
G01N 33/543 (20060101)

Foreign Application Priority Data

1979-01-09 JP

Abstract

Antigen- or antibody-bound microcapsules are employed for immunological assay of biochemical components having immunological activity. The microcapsule system provides high detection sensitivity, high accuracy and excellent reproducibility in immunological assay, without causing non-specific reaction. The microcapsules can be labelled with isotopes, enzymes, etc., for use in quantitative assays of trace amounts of biochemical components.