U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Treatment of hypertension with fluoxetine and l-5-hydroxytryptophane

Patent 4329356 Issued on May 11, 1982. Estimated Expiration Date: Icon_subject October 31, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Aryloxyphenylpropylamines in treating depression
Patent #: 4018895
Issued on: 04/19/1977
Inventor: Molloy ,   et al.

Process for promoting analgesia
Patent #: 4035511
Issued on: 07/12/1977
Inventor: Messing ,   et al.

Aryloxyphenylpropylamines for obtaining a psychotropic effect Patent #: 4194009
Issued on: 03/18/1980
Inventor: Molloy ,   et al.

Inventor

Assignee

Application

No. 06/202847 filed on 10/31/1980

US Classes:

514/419C=X bonded directly or indirectly by an acyclic carbon or carbon chain to ring carbon of the five-membered hetero ring (e.g., tryptophan, etc.) (X is chalcogen)

Examiners

Primary: Fagelson, Anna P.

Attorney, Agent or Firm

International Classes

A61K 31/403 (20060101)
A61K 31/405 (20060101)

Abstract

Fluoxetine alone or a combination of fluoxetine and l-5-hydroxytryptophan, preferably also with a peripheral decarboxylase inhibitor, is administered to hypertensive mammals to lower blood pressure.

Other References

  • Fuller, Res. Comm. in Chem. Path. & Pharm., vol. 10, No. 1, Jan. 1975, pp. 193-196
  • Fuller, Life Sci., vol. 25, 1979, pp. 1237-1242
  • Antonaccio et al., J. Pharm. Pharmac., vol. 25, 1973, pp. 495-497
  • Henning et al., Acta Pharmacol. et Toxicol., vol. 29, 1971, pp. 145-154
  • Krulich, Life Sci., vol. 17, 1975, pp. 1141-1144
  • Fuller et al., Fed. Proc., vol. 36, No. 8, Jul. 1977, pp. 2154-2158
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