Polymeric diffusion matrix containing ester derivatives of estradiol
Patent 4321252 Issued on March 23, 1982. Estimated Expiration Date: 
December 17, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 17, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesInventorsAssigneeApplicationNo. 06/217400 filed on 12/17/1980US Classes:514/182, Oxygen single bonded to a ring carbon of the cyclopentanohydrophenanthrene ring system424/449, Transdermal or percutaneous424/486, Synthetic polymer604/28, Method604/515To or from the female reproductory tractExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmInternational ClassesA61K 31/135 (20060101)A61K 9/70 (20060101) A61K 31/415 (20060101) A61K 31/565 (20060101) Foreign Application Priority Data1979-08-14 JPAbstractThere is disclosed a polymeric diffusion matrix for the sustained release of an estradiol ester by delivery to a patient requiring uterine wall maintenance or other types of estrogen therapy wherein the matrix comprises a polar plasticizer, polyvinylalcohol, polyvinylpyrrolidone, and a pharmaceutically effective amount of estradiol ester.Other References
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