Hyaluronate based compositions and cosmetic formulations containing same

Patent 4303676 Issued on December 1, 1981. Estimated Expiration Date:

March 21, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3659025

Ultrapure hyaluronic acid and the use thereof
Patent #: 4141973
Issued on: 02/27/1979
Inventor: Balazs

Method and composition for moisturizing the skin Patent #: 4151304
Issued on: 04/24/1979
Inventor: Evans

Inventor

Balazs, Endre A.

Application

No. 06/133481 filed on 03/21/1980

US Classes:

514/773, Peptide containing514/777, Carbohydrate or lignin, or derivative514/779, Algin or derivative514/781, Cellulose or derivative514/873EMOLLIENT

Examiners

Primary: Phillips, Delbert R.
Assistant: Hazel, Blondel

Attorney, Agent or Firm

Berger & Palmer

International Classes

A61K 8/72 (20060101)
A61K 8/64 (20060101)
A61K 8/73 (20060101)
C08L 5/00 (20060101)
A61K 8/30 (20060101)
C08L 5/08 (20060101)

Abstract

A water based, viscoelastic composition for use in cosmetic formulations comprising, (a) a mixture of sodium hyalfractions having different molecular weights, (b) protein which is derived from the natural material from which the hyaluronate is obtained, and (c) water. Also disclosed are cosmetic formulations comprising about 0.05-5.0% of the above composition together with an emollient, a sugar alcohol, a neutral or anionic polysaccharide, a preservative, bacteriostatic and fungistatic substance which does not react with or degrade hyaluronic acid, and water.

Other References

Chemical Abstracts, vol. 91, 1979, p. 332, Abstract No. 216677c, Ito, K., "Cosmetics"
Chemical Abstracts, vol. 91, 1979, p. 223, Abstract No. 15532c, Endo, M., et al., "Isolation and characterization of proteohyaluronic acid from human umbilical cord"