U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Tissue adhesive

Patent 4298598 Issued on November 3, 1981. Estimated Expiration Date: Icon_subject February 4, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventors

Application

No. 06/118656 filed on 02/04/1980

US Classes:

424/94.64, Serene proteinases (3.4.21) (e.g., trypsin, chymotrypsin, plasmin, thrombin, elastase, kallikrein, fibrinolysin, streptokinease, etc.)514/2, Peptide containing (e.g., protein, peptones, fibrinogen, etc.) DOAI514/21, Produced by or extracted from animal tissue514/8Glycoprotein (carbohydrate containing)

Examiners

Primary: Cacciapaglia, Frank Jr.

Attorney, Agent or Firm

International Classes

A61L 24/00 (20060101)
A61L 24/10 (20060101)

Foreign Application Priority Data

1979-02-15 AT

Abstract

A tissue adhesive on the basis of human or animal proteins has a content of factor XIII and fibrinogen, the ratio of factor XIII to fibrinogen, expressed in units of factor XIII per gram of fibrinogen, amounting to at least 80. Furthermore, it contains a plasminogen-activator-inhibitor or plasmin-inhibitor in an amount of 20 to 2,000 KIU per ml.

Other References

  • Matras et al., Wiener Medizinischen wochenschrift, No. 37, pp. 517-523 (1972)
  • Spangler et al., Wiener klinische wochenschrift, 85 (50), 827-829, (1973)
  • Spangler, Wiener klinische wochenschrift, Supplement 49, vol. 88, pp. 3-18 (1976)
  • Matras et al., Wiener klinische wochenschrift 90 (12) pp. 419-425 (Jun. 1978)
  • Stemburger, Thrombosis Research, vol. 12, No. 5, pp. 907-910, Pergammon Press (1978)
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