Patent ReferencesInventorsAssigneeApplicationNo. 06/167106 filed on 07/09/1980US Classes:514/392, Divalent chalcogen or acyclic nitrogen double bonded at 2-position, or tautomeric equivalent424/486Synthetic polymerExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmInternational ClassesA61K 31/135 (20060101)A61K 9/70 (20060101) A61K 31/415 (20060101) A61K 31/565 (20060101) Foreign Application Priority Data1979-08-14 JPAbstractThere is disclosed a polymeric diffusion matrix for the sustained release of clonidine by transdermal delivery to a patient wherein the matrix comprises a polar plasticizer, polyvinylalcohol, polyvinylpyrrolidone, and a pharmaceutically effective amount of clonidine. | |