Effervescent enteric-coated formulation of soluble form of erythromycin and therapeutic use thereof
Patent 4289751 Issued on September 15, 1981. Estimated Expiration Date: 
March 17, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
March 17, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesInventorAssigneeApplicationNo. 06/131183 filed on 03/17/1980US Classes:424/466, Effervescent424/44, Gas produced in situ by chemical reaction514/29The hetero ring has exactly 13 ring carbons (e.g., erythromycin, etc.)ExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmInternational ClassesA61K 9/46 (20060101)A61K 9/28 (20060101) AbstractImproved delivery and absorption of erythromycin in warm-blooded animals is achieved by administering thereto a non-toxic pharmaceutical effervescent enteric-coated tablet comprising:(a) an antibiotic effective amount of a non-toxic pharmaceutically acceptable soluble form of erythromycin;(b) a non-toxic pharmaceutically acceptable inert diluent; and(c) a non-toxic pharmaceutically acceptable effervescent couple acid and base; and(d) a non-toxic pharmaceutically acceptable enteric coating maintained over the tableted mixture of (a), (b), and (c) above.The subject composition is extremely useful in the treatment of bacterial infections in warm-blooded animals, particularly in the mitigation and treatment of upper and lower respiratory tract, skin and soft tissue infections of mild to moderate severity.Field of SearchGas produced in situ by chemical reaction | |
