U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Cyclosporin derivatives, their production and pharmaceutical compositions containing them

Patent 4288431 Issued on September 8, 1981. Estimated Expiration Date: Icon_subject October 12, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Dihydrocyclosporin C Patent #: 4108985
Issued on: 08/22/1978
Inventor: Ruegger ,   et al.

Inventors

Assignee

Application

No. 06/084100 filed on 10/12/1979

US Classes:

514/11, Monocyclic435/71.1, Using a micro-organism to make a protein or polypeptide530/321, Containing only normal peptide links in the ring, i.e., homodetic cyclic peptides930/190, Antibiotic930/21, Containing D-amino acid930/270Cyclic peptide or cyclic protein (See note 8)

Examiners

Primary: Phillips, Delbert R.

Attorney, Agent or Firm

International Classes

C07K 7/64 (20060101)
C07K 7/00 (20060101)
A61K 38/00 (20060101)

Foreign Application Priority Data

1978-10-18 CH

Abstract

Compounds of formula I ##STR1## selected from the group consisting of cyclosporin G, wherein A is ##STR2## dihydrocyclosporin G, wherein A is ##STR3## and isocyclosporin G, wherein A is ##STR4## are useful in treating inflammations and arthritis and as immuno-suppressant agents.

Other References

  • Traber, et al., Chem. Abstr. 87, 1977 80949A
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