Guanidinothiazole compounds, process for preparation and gastric inhibiting compositions containing them
Patent 4283408 Issued on August 11, 1981. Estimated Expiration Date: 
December 27, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 27, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPharmacologically active guanidine compounds Guanidino imidazoles and thiazoles Guanidine derivatives of imidazoles and thiazoles Patent #: 4165378 Inventors
AssigneeApplicationNo. 06/107629 filed on 12/27/1979US Classes:514/370, Nitrogen bonded directly to ring carbon of the thiazole ring548/193, Chalcogen attached indirectly to the thiazole ring by nonionic bonding548/196, Chalcogen or additional nitrogen bonded directly to the -C(=X)- group548/197Nitrogen bonded directly to chalcogenExaminersPrimary: Berch, Mark L.Attorney, Agent or FirmInternational ClassesC07D 277/48 (20060101)C07D 277/00 (20060101) C07D 277/40 (20060101) Foreign Application Priority Data1979-08-02 JPAbstractNovel guanidinothiazole compounds of the general formula ##STR1## wherein R represents a hydrogen atom or a lower alkyl group, R1 represents an amino group, a lower alkyl group, a halogeno lower alkyl group, a substituted- or unsubstituted-aryl group, a mono- or di-lower alkylamino group, an arylamino group or an aralkylamino group, R2 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group or a lower alkynyl group, Y represents a sulfur atom or a methylene group, m and n, each represents an integer of 1-3, and the pharmacologically acceptable acid addition salts thereof, they are useful as gastric acid secretion inhibitors.Other References
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