InventorsApplicationNo. 06/059859 filed on 07/23/1979US Classes:514/511, Two of the cyclos share at least three ring members (i.e., bridged)560/141, Rings bonded directly to each other in phenolic moiety560/255, Plural rings in alcohol moiety568/734Bicyclo ring systemExaminersPrimary: Mars, Howard T.Assistant: Clarke, Vera C. Attorney, Agent or FirmInternational ClassesC07C 39/23 (20060101)C07C 39/00 (20060101) C07C 39/17 (20060101) C07C 43/00 (20060101) C07C 43/178 (20060101) Foreign Application Priority Data1978-08-02 ILAbstractThe present invention relates to novel compounds of the general formula ##STR1## wherein R1 is --H or --CO--alk, wherein alk is lower alkyl of 1 to 5 carbon atoms; R2 is 1,1-dimethylheptyl or 1,2-dimethylheptyl, Q is --CH3 when A------B is a single bond, and Q is --CH2 OR4 when A------B is a double bond, and R4 is --H or --CO--alk where alk is lower alkyl of 1 to inclusive 5 carbon atoms.The invention relates both to the isomeric mixtures and to the individual isomers of the above compounds. Furthermore the invention relates to pharmaceutical compositions containing a compound defined above as active ingredient. The pharmaceutical compositions are of value as central nervous system depressants, as sedatives, as tranquilizers, as anticonvulsant agents, as effective agents against migraine, for the treatment of glaucoma, as antidiarrheal agents and as antiinflammatory agents. The invention also relates to a process for the production of the above compounds and pharmaceutical compositions.Field of SearchRings bonded directly to each other in phenolic moiety |
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