Patent References 3618604 3845201 Ocular insert Osmotic bursting drug delivery device Patent #: 4177256 InventorsAssigneeApplicationNo. 06/138150 filed on 04/07/1980US Classes:424/427OcularExaminersPrimary: Rosenbaum, C. FredAttorney, Agent or FirmInternational ClassesA61K 9/00 (20060101)A61F 9/00 (20060101) AbstractA drug delivery system is disclosed useful for controlled ocular therapy. The system is manufactured as an ocular insert, and it comprises a beta-adrenergic blocking osmotic solute and a parasympathomimetic osmotic solute dispersed in a polymer with the solutes surrounded by the polymer. The system, when placed in the eye, delivers both drugs at a controlled rate over time. A method also is disclosed for the management of intraocular pressure using the ocular system. | |