Phencyclidine conjugates to antigenic proteins and enzymes
Patent 4281065 Issued on July 28, 1981. Estimated Expiration Date: 
January 25, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
January 25, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3878187 Compounds for enzyme amplification assay methadone analogs Lysozyme conjugates for enzyme immunoassays Indirect solid surface test for antigens or antibodies Patent #: 4067959 InventorsAssigneeApplicationNo. 06/006935 filed on 01/25/1979US Classes:435/188, Stablizing an enzyme by forming a mixture, an adduct or a composition, or formation of an adduct or enzyme conjugate435/177, Enzyme or microbial cell is immobilized on or in an organic carrier435/190, Acting on CHOH group as donor (e.g., glucose oxidase, lactate dehydrogenase (1.1))435/7.9, Assay in which an enzyme present is a label436/537, Signal modification or steric inhibition436/815, TEST FOR NAMED COMPOUND OR CLASS OF COMPOUNDS436/823, IMMUNOGENIC CARRIER OR CARRIER PER SE530/345, Chemical aftertreatment, e.g., acylation, methylation, etc.530/362, Albumin530/363, Serum albumin, e.g., BSA, HSA, etc.530/369, Separation, purification or synthesis530/386, Globulins530/389.8, Binds drug, hapten, hapten-carrier complex, or specifically-identified chemical structure (e.g., theophylline, digoxin, etc.)530/405, Nitrogen containing reactant530/806ANTIGENIC PEPTIDES OR PROTEINSExaminersPrimary: Wiseman, Thomas G.Attorney, Agent or FirmInternational ClassesC07D 295/155 (20060101)C12N 9/96 (20060101) G01N 33/94 (20060101) C07D 295/00 (20060101) C07D 295/096 (20060101) G01N 33/535 (20060101) AbstractPhencylidine, PCP, derivatives having a non-oxo carbonyl functionality linked directly or through a linking group to the phenyl ring are provided for conjugation to antigenic compositions, particularly poly(amino acids), and enzymes. The antigenic conjugates are employed for the production of antibodies, which find particular use in immunoassays for the determination of phencyclidine, while the enzyme conjugate finds use in a homogeneous enzyme immunoassay for the determination of phencyclidine.Other References
Field of SearchCARRIER-BOUND OR IMMOBILIZED ENZYME OR MICROBIAL CELL; CARRIER-BOUND OR IMMOBILIZED CELL; PREPARATION THEREOFEnzyme or microbial cell is immobilized on or in an organic carrier Stablizing an enzyme by forming a mixture, an adduct or a composition, or formation of an adduct or enzyme conjugate |
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