Pharmaceutical preparation comprising a cardiac glycoside with a polymer coating
Patent 4263273 Issued on April 21, 1981. Estimated Expiration Date: December 17, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
A solid pharmaceutical preparation for administration in dosage unit form comprising a therapeutically effective cardiac glycoside, whereby each dosage unit is to comprise a plurality of bodies, each of said bodies having a pharmaceutically indifferent core, a first layer thereon containing the glycoside and a second layer containing a polymer insoluble in gastric juice and soluble in intestinal juice, a process for preparing such preparation and a method of treatment employing the same.
Other References
Bogentoft et al., Chem. Abstracts 87 #73374f (1977) abstract of Ger. Off. 2,651,176, 18 May 1977, 18 pp. based on Swed. Appl. 75/12,883, 17 Nov. 1975
Bogentoft et al., Chem. Abstracts 90, #76495u (1979), abstract of Evr. J. Clin. Pharmacol. 14(5):351-5 (1978) (Enteric Coated Granules Permit More Reproducible Absorption than Enteric Coated Tablets, When Taken with Food)