U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method and composition for the preparation of controlled long-acting pharmaceuticals

Patent 4259314 Issued on March 31, 1981. Estimated Expiration Date: Icon_subject December 10, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3424842

3776001

3845201

3868445

3870790

3875300

Solid state ophthalmic medication Patent #: 4179497
Issued on: 12/18/1979
Inventor: Cohen ,   et al.

Inventor

Application

No. 06/102227 filed on 12/10/1979

US Classes:

424/469, Discrete particles in supporting matrix514/781Cellulose or derivative

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

International Classes

A61K 9/02 (20060101)
A61K 9/20 (20060101)

Abstract

A method and composition for the preparation of controlled long-acting pharmaceuticals using a dry carrier or base material comprising an effective amount of hydroxypropyl methylcellulose and hydroxypropyl cellulose suitable for use with both hygroscopic and non-hygroscopic materials. The controlled long-acting products of the invention are suitable for use in the form of lozenges, buccal tablets, oral tablets or suppositories.

Other References

  • Forest Laboratories, Inc., Lowey H. Tablets Based on Hydroxy-Propyl Methyl Cellulose Treated by Adjusting Moisture Content to 85% Then Drying to 5% for Continuous Release of Pharmaceutical DT2718260 (11-17-77) FR2358895, J52145514
  • Lowey, H. Slow Release Compns. Based on Hydroxypropylmethyl Cellulose, NL7308859, DT2332484, FR290409, GB1430684, CA1018456, J4905419
  • Hercules, Inc., "Fact Sheet On Klucel", 2 pp. Dec. 4, 1972
  • Hercules, Inc., "Klucel Hydroxypropyl Cellulose", 32 pp. (1971)
  • Klug, J. Polymer. Sci., Part C, No. 36:491-508 (1971) "Some Properties of Water-Soluble Hydroxyalkyl Celluloses and Their Derivatives"
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