U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

4-Hydroxy-2-pyrone derivatives having antihyperlipaemic activity

Patent 4255444 Issued on March 10, 1981. Estimated Expiration Date: Icon_subject October 26, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Physiologically active substances Patent #: 3983140
Issued on: 09/28/1976
Inventor: Endo ,   et al.

Inventors

Assignee

Application

No. 06/088621 filed on 10/26/1979

US Classes:

514/460, Chalcogen bonded directly to ring carbon of the hetero ring549/292Additional chalcogen bonded directly to the lactone ring

Examiners

Primary: Jiles, Henry R.
Assistant: Fan, Jane T.

Attorney, Agent or Firm

International Classes

C07D 309/30 (20060101)
C07D 309/00 (20060101)

Foreign Application Priority Data

1978-10-30 JP

Abstract

4-Hydroxy-2-pyrone derivatives of formula (I): ##STR1## (wherein A represents an alkylene group which is optionally alkyl-substituted or an alkenylene group, and Z represents a substituted or unsubstituted aryl or aryloxy group) may be prepared by cyclizing an ester of formula (II): ##STR2## (wherein A and Z are as defined above and R represents an organic group) and have valuable antilipaemic activities.

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