U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Polyvinyl alcohol ophthalmic gel

Patent 4255415 Issued on March 10, 1981. Estimated Expiration Date: Icon_subject November 22, 1998. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2703777

2861920

3214338

3608073

3767788

Ophthalmic formulation Patent #: 4003991
Issued on: 01/18/1977
Inventor: Krohn ,   et al.

Inventors

Assignee

Application

No. 05/962812 filed on 11/22/1978

US Classes:

514/40, Two saccharide radicals bonded through only oxygen to 4- and 6- positions of the cyclohexyl ring424/606, Sodium containing or fluorine containing424/660, Borates514/179, Modified C-ring (except methyl in 13-position) (e.g., double bond containing, substituted, etc.)514/180, 9-position substituted514/397, Additional hetero ring514/402, Additional hetero ring514/669Polyhydroxy

Examiners

Primary: Robinson, Douglas W.

Attorney, Agent or Firm

International Class

A61K 9/00 (20060101)

Abstract

An ophthalmic gel having an improved intensity and duration of the biological response is provided by utilizing a polyvinyl alcohol-sodium borate gel buffered to a pH of 6.5-8.5.

Other References

  • Invest. Ophthal. Feb. (1975) 14 (2) pp. 87-89, "Ophthalmic Drug Inserts"
  • Am. J. Ophthalmol. 57 (1) pp. 99-106 (1964)-Krishna et al., PVA as an Ophthalmic Vehicle
  • Symposium on Ocular Therapy, 9 pp. 1-16 (1977), Maichuk-"Polymeric Drug Delivery Systems"
  • Japanese Published Appli. 7,131,456-Modified PVA Hydrogel Compositions-(1967)
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