U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Piperazinone and piperazine polypeptides

Patent 4251438 Issued on February 17, 1981. Estimated Expiration Date: Icon_subject June 14, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Novel-enkephalin analogs Patent #: 4103005
Issued on: 07/25/1978
Inventor: Li

Inventor

Assignee

Application

No. 06/048330 filed on 06/14/1979

US Classes:

530/302, Endorphin and Enkephalin; related peptides514/809, ENKEPHALIN OR ENDORPHIN OR DERIVATIVES530/330, 4 to 5 amino acid residues in defined sequence540/492, Plural nitrogens in the hetero ring544/373, The five-membered hetero ring is one of the cyclos in a bicyclo ring system544/384, Chalcogen bonded directly to piperazine ring carbon548/228, Chalcogen bonded directly at 5-position of the oxazole ring930/21, Containing D-amino acid930/80Endorphin or Enkephalin; related peptides

Examiners

Primary: Phillips, Delbert R.

Attorney, Agent or Firm

International Classes

C07D 243/08 (20060101)
C07D 241/00 (20060101)
C07D 241/04 (20060101)
C07D 241/08 (20060101)
C07D 243/00 (20060101)
C07K 14/70 (20060101)
C07K 5/00 (20060101)
C07K 5/107 (20060101)
C07K 14/435 (20060101)

Abstract

Piperazinone polypeptides which are useful as analgesics and psychotherapeutic agents as well as processes to produce them are described.

Other References

  • S Bajusz, et al., FEBS Letters, 76, No. 1, (1977), 91-92
  • J. M. Walker et al., "Science," (1977), 196, 85-87
  • Tomatis, et al., Ed. Sci. 34, pp. 698-703, (1979)
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