Long acting preparation of cefalexin for effective treatments of bacterial infection sensitive to cefalexin
Patent 4250166 Issued on February 10, 1981. Estimated Expiration Date: 
February 10, 1998. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 10, 1998. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References3078216 InventorsAssigneeApplicationNo. 05/801402 filed on 05/27/1977US Classes:424/419, Natural or synthetic resin514/209Alkyl, hydroxyalkyl, alkoxyalkyl, or alkanoyloxyakyl bonded directly to 3-positionExaminersPrimary: Goldberg, Jerome D.Attorney, Agent or FirmInternational ClassesA61K 9/50 (20060101)A61K 31/545 (20060101) AbstractA cefalexin preparation coated with a coating layer the solubility of which layer is pH-dependent and dissolves in the upper intestine is preferably administered concurrently with a normal (plain, quick-releasing) cefalexin. The coated preparation is preferably coated, in the particle form and when administered orally, exists in the particle form in the stomach. Preferably, the coating layer is made from a coating material having a dissolution pH of from 5.5 to 6.5, and the ratio in terms of potency of the coated cefalexin to the normal cefalexin is between 15:85 and 60:40. The coated cefalexin and the normal cefalexin can be formulated in a pharmaceutical preparation preferably in a unit-dosage form, e.g., capsules, tablets or particles or in strip-packages.Other References
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