U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Tretinoin in a gel vehicle for acne treatment

Patent 4247547 Issued on January 27, 1981. Estimated Expiration Date: Icon_subject March 19, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3729568

3867533

Inventor

Application

No. 06/022022 filed on 03/19/1979

US Classes:

514/179, Modified C-ring (except methyl in 13-position) (e.g., double bond containing, substituted, etc.)424/78.05, Anti-inflammatory or anti-irritant (e.g., anti-arthritic, etc.)514/171, With additional active ingredient514/944GEL

Examiners

Primary: Schenkman, Leonard

Attorney, Agent or Firm

International Classes

A61K 8/67 (20060101)
A61K 8/30 (20060101)

Abstract

An acne treatment gel composition, effective at low concentrations of tretinoin, is provided for topical application. The composition is highly effective in treating acne conditions and is capable of being stored without refrigeration for long periods of time without losing therapeutic effectiveness and while maintaining the uniformity and stability of the gel.

Other References

  • Konig et al., Arzneimitt-Forsch, No. 8 (1974) 1184-1187
  • Hopponen, Handbook of Non-Prescription Drugs, pp. 155-160 (1973)
  • Martin, Physical Pharmacy, pp. 623-627 (1962)
  • Physicians Desk Reference (PDR) 1968, pp. 1108 & 1214
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