Patent ReferencesMethod and apparatus for detection of antibodies and antigens Patent #: 4054646 InventorsAssigneeApplicationNo. 05/851491 filed on 11/14/1977US Classes:436/500, THYROID HORMONE TESTS (E.G., T3, T4, TBG, TSH, ETC.)310/312, Adding or subtracting mass422/57, Having coated reagent422/61, Test package or kit422/69, Sorption testing436/513, INVOLVING IGA, IGD, IGE, OR IGM436/527, Glass or silica436/806, ELECTRICAL PROPERTY OR MAGNETIC PROPERTY436/807, APPARATUS INCLUDED IN PROCESS CLAIM (E.G., PHYSICAL SUPPORT STRUCTURES, ETC.)436/808, Automated or kit436/815, TEST FOR NAMED COMPOUND OR CLASS OF COMPOUNDS436/817Steroids or hormonesExaminersPrimary: Marantz, SidneyAttorney, Agent or FirmInternational ClassesG01N 27/00 (20060101)G01N 33/543 (20060101) AbstractAn improved indirect assay and article for determining an antigen in a liquid sample. The assay utilizes a piezoelectric oscillator which has been coated with the antigen or a protein mixture containing the antigen being determined. The antigen-coated oscillator is contacted with the liquid sample and a predetermined amount of an antibody specific for the antigen being determined. The amount of free antigen in the sample, if any, can be determined by measuring the change in frequency of the oscillator following contact with the liquid sample and the antibody, and referring to a standard curve.Other References
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