U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Immunoassay for antigens

Patent 4242096 Issued on December 30, 1980. Estimated Expiration Date: Icon_subject December 30, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method and apparatus for detection of antibodies and antigens Patent #: 4054646
Issued on: 10/18/1977
Inventor: Giaever

Inventors

Assignee

Application

No. 05/851491 filed on 11/14/1977

US Classes:

436/500, THYROID HORMONE TESTS (E.G., T3, T4, TBG, TSH, ETC.)310/312, Adding or subtracting mass422/57, Having coated reagent422/61, Test package or kit422/69, Sorption testing436/513, INVOLVING IGA, IGD, IGE, OR IGM436/527, Glass or silica436/806, ELECTRICAL PROPERTY OR MAGNETIC PROPERTY436/807, APPARATUS INCLUDED IN PROCESS CLAIM (E.G., PHYSICAL SUPPORT STRUCTURES, ETC.)436/808, Automated or kit436/815, TEST FOR NAMED COMPOUND OR CLASS OF COMPOUNDS436/817Steroids or hormones

Examiners

Primary: Marantz, Sidney

Attorney, Agent or Firm

International Classes

G01N 27/00 (20060101)
G01N 33/543 (20060101)

Abstract

An improved indirect assay and article for determining an antigen in a liquid sample. The assay utilizes a piezoelectric oscillator which has been coated with the antigen or a protein mixture containing the antigen being determined. The antigen-coated oscillator is contacted with the liquid sample and a predetermined amount of an antibody specific for the antigen being determined. The amount of free antigen in the sample, if any, can be determined by measuring the change in frequency of the oscillator following contact with the liquid sample and the antibody, and referring to a standard curve.

Other References

  • Shons et al., J. Biomed. Mater. Res., 6, 565 (1972)
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