Method for the assay of classes of antigen-specific antibodies
Patent 4236893 Issued on December 2, 1980. Estimated Expiration Date: 
April 9, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 9, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3720760 Method and reagent for determining immunologic materials Indirect latex test for determination of immunoglobulins Patent #: 4092114 InventorAssigneeApplicationNo. 06/028348 filed on 04/09/1979US Classes:436/513, INVOLVING IGA, IGD, IGE, OR IGM310/312, Adding or subtracting mass422/57, Having coated reagent422/61, Test package or kit422/69, Sorption testing436/531, Carrier is synthetic resin436/808, Automated or kit436/828PROTEIN AExaminersPrimary: Marantz, SidneyAttorney, Agent or FirmInternational ClassG01N 33/543 (20060101)AbstractA method and article for the determination of a particular subclass of antibody, e.g., IgA, IgE, IgM, etc., are disclosed. The method utilizes a piezoelectric oscillator having bound to the surface thereof an antigen specific for the antibody being determined. The antigen-coated oscillator is exposed to a solution containing an unknown amount of the antibody. After the antibody in the solution has attached to the antigen on the oscillator, the oscillator is exposed to a substance (sandwiching substance) which selectively binds to a specific subclass of the antibody being determined. The frequency of the oscillator is measured before and after exposure to the sandwiching substance. The change in frequency is related to the amount of the subclass of antibody bound to the oscillator, and the amount of the subclass of antibody in the solution can be quantified by reference to a standard curve.Other References
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