Method of preparing mycophenolic acid glucoside
Patent 4234684 Issued on November 18, 1980. Estimated Expiration Date: 
December 11, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 11, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3184887 Metabolite A-27106 and processes for its preparation and use Patent #: 3932619 InventorsAssigneeApplicationNo. 06/102504 filed on 12/11/1979US Classes:435/75, Oxygen of the saccharide radical is directly bonded to a nonsaccharide heterocyclic ring or a fused- or bridged-ring system which contains a nonsaccharide heterocyclic ring (e.g., coumermycin, novobiocin, etc.)435/78, Oxygen atom of the saccharide radical is directly bonded to a condensed ring system having three or more carboxyclic rings (e.g., dauomycin, adriamycin, etc.)435/892Streptomyces candidusExaminersPrimary: Tanenholtz, Alvin E.Attorney, Agent or FirmInternational ClassesC07D 307/00 (20060101)C12P 17/04 (20060101) C12P 19/60 (20060101) C12P 19/00 (20060101) C12P 17/02 (20060101) C07D 307/88 (20060101) AbstractAn improved method of preparing mycophenolic acid glucoside which comprises contacting mycophenolic acid with glucose in an aqueous medium in the presence of a glucosylating enzyme selected from that produced by Streptomyces candidus NRRL 5449 and that produced by Streptomyces aureofaciens NRRL 2209 until mycophenolic acid glucoside is formed.Other References
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