Reagent for use in immunochemical assay methods
Patent 4232119 Issued on November 4, 1980. Estimated Expiration Date: 
March 2, 1998. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
March 2, 1998. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesEnzyme conjugates Preparation of active proteins cross-linked to inactive proteins Thiopolymers, their derivatives and methods for their preparation and use Patent #: 4048416 InventorsAssigneeApplicationNo. 05/882545 filed on 03/02/1978US Classes:530/391.5, Conjugated via a specifically-identified linking group, chelating group, coordination complex, coupling agent, or conjugation agent435/188, Stablizing an enzyme by forming a mixture, an adduct or a composition, or formation of an adduct or enzyme conjugate435/7.9, Assay in which an enzyme present is a label435/7.92, Heterogeneous or solid phase assay system (e.g., ELISA, etc.)435/964, INCLUDING ENZYME-LIGAND CONJUGATE PRODUCTION (E.G., REDUCING RATE OF NONPRODUCTIVE LINKAGE, ETC.)436/512, INVOLVING ANTIBODY FRAGMENTS436/513, INVOLVING IGA, IGD, IGE, OR IGM436/529, Polysaccharide, carrier (e.g., dextran, etc.)436/531, Carrier is synthetic resin436/543, INVOLVING PRODUCING OR TREATING ANTIGEN OR HAPTEN436/547, INVOLVING PRODUCTION OR TREATMENT OF ANTIBODY530/389.3Binds plasma protein, serum protein, or fibrin (e.g., clotting factor, fibrinolytic factor, complement factor, immunoglobulin, apolipoprotein, etc.)ExaminersPrimary: Shapiro, Lionel M.Attorney, Agent or FirmInternational ClassesA61K 39/44 (20060101)G01N 33/532 (20060101) Foreign Application Priority Data1977-03-04 SEAbstractA reagent for use in immunochemical assay methods carried out in the presence of an aqueous liquid, which reagent comprises a conjugate of one or more molecules of immunoglobulin and one or more units of an analytically indicatable group which molecules and units are bound together via bridges containing the group, --S--S--, said conjugate being soluble in said aqueous liquid. |
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