Substituted morpholine derivatives and compositions
Patent 4229449 Issued on October 21, 1980. Estimated Expiration Date: 
January 8, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
January 8, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorsApplicationNo. 06/001604 filed on 01/08/1979US Classes:514/239.2, The chalcogen is bonded directly to two carbon atoms544/148, Plural ring hetero atoms in the additional hetero ring544/162, Nitrogen attached directed or indirectly to morpholine ring by nonionic bonding544/165, Carbocyclic ring bonded directly to the nitrogen544/168, Oxygen double bonded and acyclic nitrogen bonded directly to the same carbon544/169, A ring bonded directly to the carbon544/174, Ether containing549/443, Chalcogen attached indirectly to the bicyclo ring system by nonionic bonding549/444, The chalcogen, X, is in a -C(=X)- group564/347, The ether oxygen is bonded directly to the aryl ring or ring system564/349, Alkanol group only between the amino nitrogen and the ether oxygen which is bonded directly to the aryl ring or ring system (i.e., aryloxy alkanol amines)564/360Additional hydroxy, bonded directly to carbon, or ether oxygen attached directly or indirectly to the acyclic carbon or chain by acyclic nonionic bonding with no amino nitrogen between the additional hydroxy or ether oxygen and the aryl ring or ring system (H of -OH may be replaced by a substituted or unsubstitited ammonium ion or a Group IA or IIA light metal)ExaminersPrimary: Jiles, Henry R.Assistant: Ramsuer, R. W. Attorney, Agent or FirmInternational ClassesC07C 41/00 (20060101)C07C 41/16 (20060101) C07C 43/00 (20060101) C07C 43/215 (20060101) C07C 45/00 (20060101) C07D 303/24 (20060101) C07D 303/00 (20060101) C07C 45/41 (20060101) C07C 59/00 (20060101) C07C 205/32 (20060101) C07C 205/00 (20060101) C07C 59/68 (20060101) C07D 265/33 (20060101) C07D 317/00 (20060101) C07D 317/58 (20060101) C07D 265/00 (20060101) C07D 265/30 (20060101) C07D 265/32 (20060101) C07D 295/092 (20060101) C07D 295/00 (20060101) Foreign Application Priority Data1978-01-20 ITAbstractSubstituted morpholine derivatives, such as, for instance, the compound 2-[-(2-methoxy-phenoxy)-benzyl]-morpholine are disclosed.The claimed compounds are active on the central nervous system, and may be used as antidepressant agents.Other References
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