Patent References 2726982 2949401 2980589 3034964 3065143 3251824 3424842 3852421 3870790 Process for obtaining pharmaceutical sustained releases InventorAssigneeApplicationNo. 06/048344 filed on 06/14/1979US Classes:424/469, Discrete particles in supporting matrix424/480, Cellulose or derivative514/781Cellulose or derivativeExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmInternational ClassA61K 9/20 (20060101)AbstractShaped pharmaceutical tablets, lozenges, suppositories and other solid dosage unit forms which have a prolonged and regular release pattern of a therapeutically active medicament incorporated therein, wherein the shaped dosage unit comprises a carrier base material of hydroxypropylmethylcellulose or a mixture thereof with up to 30% ethylcellulose and/or up to 30% sodium carboxymethylcellulose and wherein the carrier base material is subjected to hydrolysis and oxidation so as to generate thereon a desired minimum concentration of carbonyl and carboxyl groups, and then admixed and shaped with a therapeutically active medicament.Other References
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