U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Sustained release therapeutic compositions

Patent 4226849 Issued on October 7, 1980. Estimated Expiration Date: Icon_subject June 14, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2726982

2949401

2980589

3034964

3065143

3251824

3424842

3852421

3870790

Process for obtaining pharmaceutical sustained releases
Patent #: 3950508
Issued on: 04/13/1976
Inventor: Mony ,   et al.

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Inventor

Assignee

Application

No. 06/048344 filed on 06/14/1979

US Classes:

424/469, Discrete particles in supporting matrix424/480, Cellulose or derivative514/781Cellulose or derivative

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

International Class

A61K 9/20 (20060101)

Abstract

Shaped pharmaceutical tablets, lozenges, suppositories and other solid dosage unit forms which have a prolonged and regular release pattern of a therapeutically active medicament incorporated therein, wherein the shaped dosage unit comprises a carrier base material of hydroxypropylmethylcellulose or a mixture thereof with up to 30% ethylcellulose and/or up to 30% sodium carboxymethylcellulose and wherein the carrier base material is subjected to hydrolysis and oxidation so as to generate thereon a desired minimum concentration of carbonyl and carboxyl groups, and then admixed and shaped with a therapeutically active medicament.

Other References

  • Forest Laboratories, Inc., Lowey, H. Tablets based on Hydroxypropyl Methyl Cellulose Treated by Adjusting Moisture Content to 85 percent then drying to 5 percent for Continuous Release of Pharmaceutical, DT 2718260, SW 7704764, J 52145514, BR 7702882, FR 2358895
  • Lowey H., Slow Release Compnds, based on Hydroxypropylmethyl Cellulose, NL 7308859-DT 2332484-FR 2190409-J 49054519-GB 1430684
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