U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

System with microporous reservoir having surface for diffusional delivery of agent

Patent 4217898 Issued on August 19, 1980. Estimated Expiration Date: Icon_subject October 23, 1998. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2478182

2846057

2928770

2987445

3146169

3538214

Novel drug permeable wall
Patent #: 3938515
Issued on: 02/17/1976
Inventor: Leeper ,   et al.

Novel drug delivery device
Patent #: 3948254
Issued on: 04/06/1976
Inventor: Zaffaroni

Osmotic device having microporous reservoir Patent #: 3977404
Issued on: 08/31/1976
Inventor: Theeuwes

Inventor

Application

No. 05/953907 filed on 10/23/1978

US Classes:

424/433, Depot, pellet, matrix, or suppository424/427, Ocular424/436, Anal, rectal (e.g., suppositories, etc.)424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/486Synthetic polymer

Examiners

Primary: Rosenbaum, C. Fred

Attorney, Agent or Firm

International Classes

A61K 9/00 (20060101)
A61M 31/00 (20060101)

Abstract

A system is disclosed for delivering an active agent to a fluid environment of use. The system comprises a microporous reservoir, an active agent housed in the reservoir, a surface that defines an exposed area of the reservoir for releasing agent from the reservoir to the environment, and a wall impermeable to both fluid and agent that surrounds the remaining, unexposed surfaces of the reservoir. In operation, when the system is in the environment with the exposed surface presented to fluid, fluid enters the system through the exposed surface causing agent to diffuse from within the system, which agent is released from the exposed surface of the system to the environment at a controlled rate over time.

Other References

  • Acta Pharm. Suecia, vol. 8, pp. 153-168, 1971, Sjorgen
  • J. Pharm. Sci., vol. 60, pp. 1028-1033, 1971, Arcy et al
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