Compositions containing aqueous dispersions of lipid spheres
Patent 4217344 Issued on August 12, 1980. Estimated Expiration Date: 
December 29, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 29, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 1959930 2853423 2949403 3041289 3630920 3686701 Liposome encapsulation of chelating agents Moisturizing units and moisturizing compositions containing the same Patent #: 3957971 InventorsAssigneeApplicationNo. 05/865499 filed on 12/29/1977US Classes:424/60, Aromatic acid or derivative containing (e.g., aminobenzoic acid or methyl salicylate, etc.)264/4.1, Liquid encapsulation utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome)424/450, Liposomes424/59, TOPICAL SUN OR RADIATION SCREENING, OR TANNING PREPARATIONS424/62, BLEACH FOR LIVE HAIR OR SKIN (E.G., PEROXIDES, ETC.)424/63, LIVE SKIN COLORANT CONTAINING426/89, SURFACE COATED, FLUID ENCAPSULATED, LAMINATED SOLID COMPOSITE OF SELF SUSTAINING DISSIMILAR EDIBLE MATERIAL428/402.2, Microcapsule with fluid core (includes liposome)428/402.24, Microcapsule with solid core (includes liposome)512/4, Nonliquid or encapsulated514/474Ascorbic acid or derivative (e.g., vitamin C, etc.)ExaminersPrimary: Lovering, Richard D.Attorney, Agent or FirmInternational ClassesA61K 9/127 (20060101)A61K 8/14 (20060101) A61Q 19/04 (20060101) Foreign Application Priority Data1976-06-23 BEAbstractThe present invention relates to a process for producing a dispersion of spheres comprising arranged molecular layers encapsulating an aqueous phase. The process comprises admixing a water-dispersible lipid component with the aqueous phase to be encapsulated, the liphophile/hydrophile ratio of the lipid component being such that the lipid swells in the said aqueous phase so as to form a lamellar phase. The lamellar phase is agitated and there is added thereto a dispersion liquid in an amount greater than the resulting lamellar phase and the resulting mixture is vigorously agitated for a period of time ranging from 15 minutes to 3-4 hours. The spheres can encapsulate a water-soluble pharmaceutical, a cosmetic or a food and the dispersions containing said encapsulated materials can be used particularly in the pharmaceutical and cosmetic fields.Other References
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