Glycoprotein and process for isolating it
Patent 4217339 Issued on August 12, 1980. Estimated Expiration Date: 
May 4, 1998. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 4, 1998. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesProcess for extracting and processing glycoproteins, mucopolysaccharides and accompanying substances Patent #: 4108849 InventorsAssigneeApplicationNo. 05/903006 filed on 05/04/1978US Classes:436/543, INVOLVING PRODUCING OR TREATING ANTIGEN OR HAPTEN424/531, Serum424/583, Placenta or umbilical cord435/212, Acting on peptide bond (e.g., thromboplastin, leucine amino-peptidase, etc., (3.4))435/217, Plasmin (i.e., fibrinolysin)435/219, Proteinase435/226, Derived from animal tissue (e.g., rennin, etc.)436/547, INVOLVING PRODUCTION OR TREATMENT OF ANTIBODY436/814, Pregnancy530/386, Globulins530/392, Alpha globulins, e.g., ceruloplastin, haptoglobins, etc.530/395, Glycoprotein, e.g., mucins proteoglycans, etc.530/412, Separation or purification530/413, Immunological separation or affinity chromatography530/416, Ion exchange530/830, Plasma; serum530/851Placenta; amniotic fluidExaminersPrimary: Shapiro, Lionel M.Attorney, Agent or FirmInternational ClassesA61K 35/16 (20060101)A61K 35/48 (20060101) A61K 35/50 (20060101) C07K 14/47 (20060101) C07K 14/435 (20060101) G01N 33/531 (20060101) A61K 38/00 (20060101) A61K 39/00 (20060101) Foreign Application Priority Data1977-05-07 DEAbstractWhat is disclosed is a glycoprotein having proteolytic, fibrinolytic, and thrombolytic properties and which can be used to prepare anti-sera useful as diagnostic agents, said glycoprotein being found in human blood serum and extracts of human placentas and being capable of isolation therefrom and which has the following properties:a protein proportion essentially consisting of 89&#b1;4% of -amino-acids,a carbohydrate proportion of 11.1&#b1;2.2%, among it 5.3&#b1;1.1% of hexoses, 2.8&#b1;0.5 N of N-acetylated hexosamine, 2.9&#b1;0.6% of N-acetylated neuraminic acid;a sedimentation coefficient S20x of 3.2&#b1;0.3 S;a molecular weight of 32 000&#b1;6 000;an iso-electric point at pH 4.3&#b1;0.3;an extinction coefficient E1 cm1% (280 nm) of 13.8&#b1;1.0;an electrophoretic mobility in the range between that of albumin and 댑 -globulins;a specific immunologic reaction with an antibody specifically directed against the protein, anda proteolytic activity, as well as a process for isolating it.Other References
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