U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Device having variable volume chamber for dispensing useful agent

Patent 4203440 Issued on May 20, 1980. Estimated Expiration Date: Icon_subject October 23, 1998. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3760984

3865108

Method and apparatus for introducing fluids into the body
Patent #: 3971376
Issued on: 07/27/1976
Inventor: Wichterle

Rotary piston type engine
Patent #: 3987760
Issued on: 10/26/1976
Inventor: Kanaoka

Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient Patent #: 3995631
Issued on: 12/07/1976
Inventor: Higuchi ,   et al.

Inventor

Application

No. 05/953489 filed on 10/23/1978

US Classes:

604/892.1, Osmotic or diffusion pumped device or system222/386.5Nonrigid follower

Examiners

Primary: Michell, Robert W.
Assistant: Rosenbaum, C. Fred

Attorney, Agent or Firm

International Class

A61K 9/00 (20060101)

Abstract

A self-powered device is disclosed for delivering a useful agent. The device comprises (1) a housing member, (2) a variable volume chamber storing a useful agent and having a passageway for delivering the agent in the housing, and (3) a pressure generating member comprising a semipermeable polymer having a cross-linked hydrophilic polymer dispersed therein positioned between the housing and the chamber. In operation, when the device is in a fluid environment, fluid from the environment enters the housing and is imbibed by the hydrophilic polymer into the generator, causing the generator to enlarge and apply pressure against the chamber, thereby decreasing the volume of the chamber and simultaneously dispensing agent through the passageway from the device at a controlled rate over a prolonged period of time. An article of manufacture also is disclosed which consists of a pressure generating member manufactured as a film useful for making a dispensing device.

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