Patent References 3760984 3865108 Method and apparatus for introducing fluids into the body Rotary piston type engine Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient Patent #: 3995631 InventorApplicationNo. 05/953489 filed on 10/23/1978US Classes:604/892.1, Osmotic or diffusion pumped device or system222/386.5Nonrigid followerExaminersPrimary: Michell, Robert W.Assistant: Rosenbaum, C. Fred Attorney, Agent or FirmInternational ClassA61K 9/00 (20060101)AbstractA self-powered device is disclosed for delivering a useful agent. The device comprises (1) a housing member, (2) a variable volume chamber storing a useful agent and having a passageway for delivering the agent in the housing, and (3) a pressure generating member comprising a semipermeable polymer having a cross-linked hydrophilic polymer dispersed therein positioned between the housing and the chamber. In operation, when the device is in a fluid environment, fluid from the environment enters the housing and is imbibed by the hydrophilic polymer into the generator, causing the generator to enlarge and apply pressure against the chamber, thereby decreasing the volume of the chamber and simultaneously dispensing agent through the passageway from the device at a controlled rate over a prolonged period of time. An article of manufacture also is disclosed which consists of a pressure generating member manufactured as a film useful for making a dispensing device. | |