U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Tetrahydrocannabinol in a method of treating glaucoma

Patent 4189491 Issued on February 19, 1980. Estimated Expiration Date: Icon_subject February 19, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3668224

3728360

3734930

3799946

3920809

Tri-cyclic compounds derived from thiaphloroglucinol ethers Patent #: 4025536
Issued on: 05/24/1977
Inventor: Korte ,   et al.

Inventors

Application

No. 05/751079 filed on 12/16/1976

US Classes:

514/397, Additional hetero ring514/913Glaucoma

Examiners

Primary: Robinson, Douglas W.

Attorney, Agent or Firm

International Class

A61K 31/35 (20060101)

Abstract

Significant success in alleviating the symptoms of glaucoma is achieved by orally administering to a glaucoma sufferer a therapeutically effective, but sub-psychotropic dose of tetrahydrocannabinol (THC), which is the most active ingredient in marijuana. The most significant results are achieved when this form of treatment is combined with conventional types of anti-glaucoma treatment, although in a limited number of cases, THC therapy alone proved successful. Also disclosed is a dosage unit form for THC comprising a suitable dose of THC in combination with an innocuous diluent such as fructose.

Other References

  • The Merck Index, 8th ed. pp. 830, 831 and 833 (1968) Merck & Co
  • Ophthalmologica 168 366-369 (1974)--D. Shapiro--The Ocular Manifestations of the Cannabinols, Newsweek, 11/8/76, Pot and Glaucoma
  • Chem. Abst. 83 158,044(r) (1975)--Purnell et al. "A9 -Tetrahydrocannabinol . . . in Man"
  • Chem. Abst. 84 130,270(h) (1976)--Green et al. Interaction of . . . Tetrahydrocannabinol in the Eye"
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