U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Means for administering amphipathic medicament

Patent 4182330 Issued on January 8, 1980. Estimated Expiration Date: Icon_subject July 25, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3845770

3926188

Controlled release delivery system by an osmotic bursting mechanism
Patent #: 3952741
Issued on: 04/27/1976
Inventor: Baker

Osmotic system having laminar arrangement for programming delivery of active agent
Patent #: 4008719
Issued on: 02/22/1977
Inventor: Theeuwes ,   et al.

Laminated osmotic system for dispensing beneficial agent
Patent #: 4014334
Issued on: 03/29/1977
Inventor: Theeuwes ,   et al.

Osmotic releasing device having a plurality of release rate patterns Patent #: 4036227
Issued on: 07/19/1977
Inventor: Zaffaroni ,   et al.

Inventor

Application

No. 05/818292 filed on 07/25/1977

US Classes:

424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/424, Membrane or diffusion barrier424/449, Transdermal or percutaneous424/450Liposomes

Examiners

Primary: Michell, Robert W.
Assistant: Rosenbaum, C. Fred

Attorney, Agent or Firm

International Classes

A61K 9/00 (20060101)
A61K 9/107 (20060101)

Abstract

Means for administering an amphipathic medicament by micelle solubilization is disclosed. The micelle consists of a nonionic surfactant medicament adduct. The adduct is coated onto an osmotically effective solute and housed in an osmotic therapeutic system for administering the medicament in a therapeutically effective amount over a prolonged period of time.

Other References

  • The Pharmacological Basis of Therapeutics, 1970, 4th Ed., pp. 677-708
  • Pharmaceutical Sciences, 1970, 14th Ed., pp. 858-864
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