Patent References 3845770 3926188 Controlled release delivery system by an osmotic bursting mechanism Osmotic system having laminar arrangement for programming delivery of active agent Laminated osmotic system for dispensing beneficial agent Osmotic releasing device having a plurality of release rate patterns Patent #: 4036227 InventorApplicationNo. 05/818292 filed on 07/25/1977US Classes:424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/424, Membrane or diffusion barrier424/449, Transdermal or percutaneous424/450LiposomesExaminersPrimary: Michell, Robert W.Assistant: Rosenbaum, C. Fred Attorney, Agent or FirmInternational ClassesA61K 9/00 (20060101)A61K 9/107 (20060101) AbstractMeans for administering an amphipathic medicament by micelle solubilization is disclosed. The micelle consists of a nonionic surfactant medicament adduct. The adduct is coated onto an osmotically effective solute and housed in an osmotic therapeutic system for administering the medicament in a therapeutically effective amount over a prolonged period of time.Other References
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