Patent References 2811483 2953497 2996431 3079303 3081233 3089824 3619294 3639169 Process for the preparation of granules Pharmaceutical compositions InventorsAssigneeApplicationNo. 05/923933 filed on 07/13/1978US Classes:424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)264/209.1, Hollow article424/439, Food or edible as carrier for pharmaceutical427/2.15, Fluidized bed utilized514/197, 6-position substituent contains carbocyclic ring514/777Carbohydrate or lignin, or derivativeExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmInternational ClassesA61K 9/16 (20060101)A61K 31/429 (20060101) A61K 31/43 (20060101) Foreign Application Priority Data1976-01-02 GBAbstractTwo, preferably three, layered orally administrable granules containing orally administrable penicillins have desirable properties such as elegance, freedom from dust and good reconstitution. They contain an inert core, preferably of sucrose, a penicillin/binder first layer and normally and preferably a final coating layer of conventional additives such as dyes, flavors etc..Preferably the penicillin is amoxycillin trihydrate and the binder sucrose. The granules may be prepared by fluid bed granulation. | |