Patent References 2816062 3679794 3852421 Method of coating pharmaceutical solid dosage forms Patent #: 4001390 InventorsAssigneeApplicationNo. 05/803853 filed on 06/06/1977US Classes:424/480, Cellulose or derivative424/479, Containing polysaccharide (e.g., sugar, etc.)427/2.18En masse rotating means employed (e.g., rotating pan, tumbling)ExaminersPrimary: Silverberg, SamAttorney, Agent or FirmInternational ClassA61K 9/28 (20060101)Foreign Application Priority Data1976-06-09 JPAbstractThe sugar-coated solid dosage forms have improved disintegrability even in a neutral medium after prolonged storage, with sugar-coating layers having excellent mechanical strengths. The coating layer that is in direct contact with the surface of the solid dosage form contains a water-insoluble hydroxypropyl cellulose with a relatively low content of hydroxypropoxy groups, say, from 4 to 16% by weight. The hydroxypropyl cellulose is used by being suspended in the coating syrup or mixed in the dusting powder for purposes of subcoating. It is also possible to use the hydroxypropyl cellulose in the form of suspension to form a smoothing coat. | |