U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Sugar-coated solid dosage forms

Patent 4176175 Issued on November 27, 1979. Estimated Expiration Date: Icon_subject June 6, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2816062

3679794

3852421

Method of coating pharmaceutical solid dosage forms Patent #: 4001390
Issued on: 01/04/1977
Inventor: Ohno ,   et al.

Inventors

Assignee

Application

No. 05/803853 filed on 06/06/1977

US Classes:

424/480, Cellulose or derivative424/479, Containing polysaccharide (e.g., sugar, etc.)427/2.18En masse rotating means employed (e.g., rotating pan, tumbling)

Examiners

Primary: Silverberg, Sam

Attorney, Agent or Firm

International Class

A61K 9/28 (20060101)

Foreign Application Priority Data

1976-06-09 JP

Abstract

The sugar-coated solid dosage forms have improved disintegrability even in a neutral medium after prolonged storage, with sugar-coating layers having excellent mechanical strengths. The coating layer that is in direct contact with the surface of the solid dosage form contains a water-insoluble hydroxypropyl cellulose with a relatively low content of hydroxypropoxy groups, say, from 4 to 16% by weight. The hydroxypropyl cellulose is used by being suspended in the coating syrup or mixed in the dusting powder for purposes of subcoating. It is also possible to use the hydroxypropyl cellulose in the form of suspension to form a smoothing coat.

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