Ophthalmic use of collagenase
Patent 4174389 Issued on November 13, 1979. Estimated Expiration Date: 
May 13, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 13, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorApplicationNo. 05/796807 filed on 05/13/1977US Classes:424/94.67Metalloproteinases (3.4.24) (e.g., collagenase, snake venom zinc proteinase, etc.)ExaminersPrimary: Rosen, SamAttorney, Agent or FirmInternational ClassesA61K 38/43 (20060101)A61K 38/48 (20060101) AbstractA method for the selective lysis of collagen fibrils located in the ocular region of a mammal comprising injecting into said ocular region an effective amount of a pharmacologically suitable solution comprising collagenase; and contacting said fibrils with said solution for a period of time sufficient to lyse said fibrils.Other References
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