U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Sustained release indomethacin

Patent 4173626 Issued on November 6, 1979. Estimated Expiration Date: Icon_subject December 11, 1998. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Inventors

Assignee

Application

No. 05/968608 filed on 12/11/1978

US Classes:

424/462, Containing solid synthetic polymers424/456, Gelatin424/497, Containing solid synthetic polymers424/499Contains proteins or derivative or polysaccharides or derivative

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

International Classes

A61K 9/50 (20060101)
A61K 31/403 (20060101)
A61K 31/405 (20060101)

Abstract

A sustained release indomethacin pharmaceutical product is provided that utilizes a pellet formulation encapsulated in a hard gelatin capsule. A portion of the pellets is uncoated for immediate and rapid release of indomethacin for elevating the plasma level. The remainder of the pellets are coated with a polymer to sustain the plasma level. The uncoated and coated pellets may be mixed with non-medicated pellets as a capsule filler.

Other References

  • Dittgen et al., Pharmazie, 1977, 32(3)185, in Chem. Abstr. 87:11555g (1977)
  • Garcia, Diss. Abstr. Int. B, 1977, 38(2):602-603 in Chem. Abstr. 87:161724a (1977)
  • Dittgen et al., Gyogyszereszet, 1976, 20(7):260-262, in Chem. Abstr. 87:189376n (1977)
  • Kala et al., Pharmazie, 1976 31(11):793-799, in Chem. Abstr. 86:60497c (1977)
  • Dittgen et al., Gyogyszereszet, 1976, 20(7):260-262, in Chem. Abstr. 85:198123p (1976)
  • Data Sheet-Indocid.RTM.-R-Sustained Release Indomethacin Remington's Pharmaceutical Sciences, 14th Ed. 1970:1699-1714, Mack Pub., Easton, Pa. 18042
  • Elanco Products Co., Div. Eli Lilly & Co., "A Great Shape for your Product", P.O. Box 1750, Indianapolis, Ind. 46206
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