13-Halo and 13-deoxy C-076 compounds
Patent 4171314 Issued on October 16, 1979. Estimated Expiration Date: 
December 19, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 19, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesAntibiotic substances Patent #: 3950360 InventorsAssigneeApplicationNo. 05/861810 filed on 12/19/1977US Classes:549/264, Spiro536/7.1Oxygen containing hetero ring having 12-19 members (e.g., methymycin, carbomycin, spiramycin, etc.)ExaminersPrimary: Trousof, NatalieAssistant: Fan, Jane T. Attorney, Agent or FirmInternational ClassesA01N 43/22 (20060101)A01N 43/02 (20060101) C07D 493/22 (20060101) C12P 19/00 (20060101) C12P 19/62 (20060101) C07F 7/00 (20060101) C07F 7/18 (20060101) C07H 17/00 (20060101) C07H 17/08 (20060101) C07D 493/00 (20060101) AbstractDerivatives of the C-076 compounds are disclosed wherein the 13-position is unsubstituted or substituted by a halogen atom. The compounds are prepared by removing the glycosyl groups on the 13-position of the C-076 compounds isolated from the fermentation broth of Streptomyces avermitilis. This is followed by substitution of the 13-hydroxy group with a halogen, and subsequent removal of the halogen. The disclosed compounds are antiparasitic, anthelmintic, insecticidal and acaracidal agents.Other References
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