ApplicationNo. 05/831817 filed on 09/09/1977
US Classes:435/7.9, Assay in which an enzyme present is a label435/188, Stablizing an enzyme by forming a mixture, an adduct or a composition, or formation of an adduct or enzyme conjugate435/7.92, Heterogeneous or solid phase assay system (e.g., ELISA, etc.)435/7.93, Competitive assay435/963METHODS OF STOPPING AN ENZYME REACTION OR STABILIZING THE TEST MATERIALS
ExaminersPrimary: Naff, David M.
Attorney, Agent or Firm
International ClassesA61K 38/44 (20060101)
A61K 38/43 (20060101)
C12N 9/96 (20060101)
C12Q 1/28 (20060101)
Foreign Application Priority Data1976-09-24 NL
AbstractNew and useful stable peroxidase compositions are disclosed which are particularly useful as reagents in enzyme immunoassay (EIA) tests. The novel peroxidase compositions contain polyvalent ions of groups 3 and 4 of the Periodic Table. These novel compositions are stable even in low concentrations, and are relatively invulnerable to freeze-drying. Preferably, the polyvalent ions selected are those of Al, Zn, Mg, Fe, and Cu.