Sample concentrator

Patent 4159933 Issued on July 3, 1979. Estimated Expiration Date:

March 25, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3470080

3533933

3579433

3616454

3640813

3674678

3720593

Inventors

Allington, William B. (deceased)NE: Nelson; James W.; Lincoln, ;
Cordry, Arthur L.
McCullough, Gail A.
Mitchell, Don E.

Assignee

Instrumentation Specialties Company

Application

No. 05/781176 filed on 03/25/1977

US Classes:

204/543, Biological material prepared, recovered, or treated (e.g., urine, etc.)204/544, Organic material prepared, recovered, or treated436/177, Liberation or purification of sample or separation of material from a sample (e.g., filtering, centrifuging, etc.)436/516Immunoelectrophoresis

Examiners

Primary: Prescott, Arthur C.

Attorney, Agent or Firm

Carney; Vincent L.

International Classes

B01D 57/02 (20060101)
B01D 57/02 (20060101)
G01N 27/447 (20060101)
G01N 27/447 (20060101)
G01N 1/34 (20060101)
G01N 1/34 (20060101)
G01N 1/40 (20060101)
G01N 1/40 (20060101)

Abstract

To concentrate a material by separating it from a diluting medium, the combination of the material and medium is placed in one of two wells in the bottom of a plastic sample concentrator cell, with each well being closed at its bottom end by a different cellophane membrane in contact with a buffer solution in a different one of two buffer compartments. A buffer solution also connects the combination of material and medium in one well and the cellophane bottom of the other well within the sample concentration cell through a recess in the bottom of the sample concentration cell. A potential is applied across the two buffer compartments to cause the material to migrate by electrophoresis from the medium in one well, through the buffer in the sample concentrating cell and into the other well, where it is concentrated against the cellophane membrane for easy removal by pipetting.