Process and apparatus for pulse labelling protein material in the Edman degradation process
Patent 4153416 Issued on May 8, 1979. Estimated Expiration Date: 
June 6, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 6, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3531258 3557077 3647390 3725010 InventorsApplicationNo. 05/803689 filed on 06/06/1977US Classes:436/57, INCLUDING USE OF RADIOACTIVE PROPERTIES422/67, With specific analytical program control means422/71, With radioactive material436/90, Alpha or beta amino acid530/344Separation or purificationExaminersPrimary: Serwin, R. E.International ClassesG01N 33/68 (20060101)G01N 33/60 (20060101) AbstractA process and apparatus for pulse labelling protein material for high sensitivitiy sequence analysis of protein material by Edman degradation technique comprising an isolated, auxiliary unit for storing a radioactive coupling reagent together with tubes, valves and controls for interrupting the Edman process, for pumping a measure of radioactive coupling reagent into the reaction vessel, a timer for controlling duration of contact between the radioactive reagent, and the protein material to maximize the coupling reaction therebetween, and thereafter reactivating the Edman process to admit nonradioactive coupling reagent to the vessel and to drive the coupling reaction to completion. |
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