U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents

Patent 4133814 Issued on January 9, 1979. Estimated Expiration Date: Icon_subject September 17, 1996. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Substituted benzofurans and benzothiophenes
Patent #: 3947470
Issued on: 03/30/1976
Inventor: Brenner ,   et al.

Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes
Patent #: 3983245
Issued on: 09/28/1976
Inventor: Ladd ,   et al.

Substituted benzofurans and benzothiophenes
Patent #: 4001426
Issued on: 01/04/1977
Inventor: Brenner ,   et al.

Benzothiophene compounds and the production and use thereof Patent #: 4007204
Issued on: 02/08/1977
Inventor: Descamps ,   et al.

Inventors

Assignee

Application

No. 05/724203 filed on 09/17/1976

US Classes:

548/525, Polycyclo ring system which includes ring chalcogen514/841, CONTRACEPTIVE544/146, Thiophene ring (including hydrogenated)546/202, Ring sulfur in the polycyclo ring system548/523, Ring nitrogens of the two nitrogen containing hetero rings are bonded directly to the same atom or chain, which chain may include a ring548/575, Carbocyclic ring bonded directly to the chalcogen549/44, Chalcogen attached directly to the tricyclo ring system by nonionic bonding549/51, Chalcogen attached directly to the bicyclo ring system by nonionic bonding549/52, Chalcogen attached directly to the hetero ring by nonionic bonding549/53, Chalcogen attached directly to ring sulfur of the hetero ring by nonionic bonding549/54, Plural chalcogens bonded directly to the bicyclo ring system549/57, Nitrogen or a -C(=X)- group, wherein X is chalcogen, attached directly to the bicyclo ring system by nonionic bonding562/431, Carboxyl, or salt thereof, in side chain having sulfur bonded directly to a ring562/843, Carbonyl bonded directly to the carbonyl group (e.g., oxalyl chlorides, etc.)562/868Nitrogen attached indirectly to the carbonyl group by nonionic bonding

Examiners

Primary: Rizzo, Nicholas S.
Assistant: Berch, Mark L.

Attorney, Agent or Firm

International Classes

C07D 333/00 (20060101)
C07D 333/68 (20060101)
C07D 333/54 (20060101)
C07D 333/56 (20060101)
C07D 295/092 (20060101)
C07D 333/64 (20060101)
C07D 295/00 (20060101)

Abstract

Derivatives of 2-phenyl-3-aroylbenzothiophenes and 2-phenyl-3-aroylbenzothiophene-1-oxides are useful as antifertility agents. Certain of these compounds also are useful in suppressing the growth of mammary tumors.

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