U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Anti-plaque agents

Patent 4130637 Issued on December 19, 1978. Estimated Expiration Date: Icon_subject October 3, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3617439

Inventor

Application

No. 05/839154 filed on 10/03/1977

US Classes:

424/54, Ammonia, amine, or derivative thereof (e.g., urea, etc.)424/52, Fluorine or fluorine compound containing424/57, Phosphate compound containing436/907FETAL LUNG MATURITY

Examiners

Primary: Rose, Shep K.
Assistant: Eakin, M. C.

Attorney, Agent or Firm

International Classes

A61K 8/44 (20060101)
A61K 8/30 (20060101)
A61Q 11/00 (20060101)

Abstract

Novel betaine compounds derived from higher alkyl dimethyl carboxylic acid quaternary ammonium compounds; the process of preparing said betaines; and compositions containing an effective antimicrobial amount of said betaines admixed with a pharmaceutical carrier. These compounds are effective in controlling dental plaque without producing an esthetically unacceptable discoloration of tooth surfaces.

Other References

  • Swain et al, Journal of Organic Chemistry, 18, 1087-1091 (1953), "Synthesis of N-Alkyldimethyl Derivatives of W-Amino Acids"
  • Accepted Dental Therapeutics, 35th edition, (1973) RK 701 A3; pp. 60-64, 193-194, 227-236
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