Diagnostic method employing a mixture of normally separable protein-coated particles
Patent 4115535 Issued on September 19, 1978. Estimated Expiration Date: 
June 22, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 22, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3853987 Solid phase radioimmunoassay of digoxin Diagnostic method and device employing protein-coated magnetic particles Patent #: 4018886 InventorApplicationNo. 05/809005 filed on 06/22/1977US Classes:436/526, Magnetic436/523, Carrier is particulate and the particles are of intentionally different sizes or impregnated differently with the immunochemicals436/525, Metal or metal coated436/527, Glass or silica436/531, Carrier is synthetic resin436/804, RADIOISOTOPE (E.G., RADIOIMMUNOASSAY, ETC.)436/805, OPTICAL PROPERTY436/806, ELECTRICAL PROPERTY OR MAGNETIC PROPERTY436/814, Pregnancy436/818Human chorionic gonadotropinExaminersPrimary: Padgett, Benjamin R.Assistant: Nucker, Christine M. Attorney, Agent or FirmInternational ClassesG01N 33/543 (20060101)G01N 33/58 (20060101) G01N 33/76 (20060101) G01N 33/74 (20060101) AbstractA mixture of two different kinds of particles having distinctive, different properties is employed for determining the presence of a select protein in, or the absence of a select protein from, a solution. The first kind of particle provides a property facilitating separation, while the second kind of particle provides a property facilitating detection. The particles are coated with the same protein, a protein able to interact specifically with the select protein. |
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