Procedure for obtaining penicillium species mutants with improved ability to synthesize mycophenolic acid
Patent 4115197 Issued on September 19, 1978. Estimated Expiration Date: 
August 29, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
August 29, 1997. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorsAssigneeApplicationNo. 05/828392 filed on 08/29/1977US Classes:435/123, Oxygen as only ring hetero atom435/441, Mutation employing a chemical mutagenic agent435/444, By use of alkylating agent (e.g., nitrosoguanidine, etc.)435/445, By use of oxidative deamination agent (e.g., nitrous acid, etc.)435/448, Ultraviolet irradiation435/933PenicilliumExaminersPrimary: Shapiro, Lionel M.Attorney, Agent or FirmInternational ClassesC12P 17/04 (20060101)C12P 17/02 (20060101) AbstractA procedure for efficiently obtaining higher mycophenolic-acid-producing mutants from mycophenolic-acid-producing strains of the genus Penicillium by selecting mutants which are resistant to polyene antibiotics.Other References
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