1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocines
Patent 4105659 Issued on August 8, 1978. Estimated Expiration Date: 
August 8, 1995. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
August 8, 1995. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3250678 3723440 InventorAssigneeApplicationNo. 04/342768 filed on 02/05/1964US Classes:546/97, Two of the cyclos share at least three ring carbons (e.g., benzomorphans, etc.)514/823, ANTIDOTE546/249, Process of forming partially hydrogenated pyridine ring546/314Carbonyl bonded directly to the six-membered hetero ringExaminersPrimary: Randolph, John D.Attorney, Agent or FirmInternational ClassesA61K 31/395 (20060101)C07D 401/00 (20060101) C07D 221/00 (20060101) C07D 221/26 (20060101) C07D 401/06 (20060101) Abstract1,2,3,4,5,6-Hexahydro-3-lower alkenyl-6-(R1)-11-(R2)-8-hydroxy-2,6-methano-3-benzazocines, wherein R1 and R2 are hydrogen or lower alkyl, and certain ethers and esters thereof, are obtained from analogous 3-unsubstituted compounds. The products have pharmacodynamic activity and are useful as antagonists of strong analgesic agents, such as morphine and meperidine, and are useful in humans as agents for producing analgesia. |
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