ApplicationNo. 05/756016 filed on 01/03/1977
US Classes:424/52, Fluorine or fluorine compound containing544/124, Six-membered ring consisting of one nitrogen and five carbons (e.g., pyridine, etc.)546/316, Acyclic nitrogen bonded directly to the carbonyl546/318, The carbonyl is in a -COO- group546/323, Acyclic nitrogen bonded directly to the carbonyl546/326, The carbonyl is in a -COO- group546/344The chalcogen is in an -OH or -OM group (M is Group IA or Group IIA light metal)
ExaminersPrimary: Rotman, Alan L.
Attorney, Agent or Firm
International ClassesC07D 213/30 (20060101)
C07D 213/00 (20060101)
C07D 213/80 (20060101)
C07D 213/82 (20060101)
AbstractThe present invention relates to new chemical compounds which can be used as inhibitors of dental plaque, and orally-acceptable compositions thereof, combinations thereof with known compounds having an inhibitory action on the formation of dental plaque, such as biguanidines, and method of treating therewith for the prevention of dental plaque or tartar and dental caries.The new compounds have the general formula ##STR1## in which R1 = H or alkylR2 = ch2 oh, alkyl carboxylate, ##STR2## and R2 is in 2 or 3 position.Compositions containing these active principles are useful in particular in the preventive treatment of periodontopathies and odontopathies and in the field of oral-dental hygiene.