U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method of enhancing the administration of pharmalogically active agents

Patent 4073943 Issued on February 14, 1978. Estimated Expiration Date: Icon_subject February 14, 1995. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2303236

2867565

2972565

2988484

3089823

3169094

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3240670

3384545

Inventors

Assignee

Application

No. 05/666264 filed on 03/12/1976

US Classes:

514/772, DESIGNATED ORGANIC NONACTIVE INGREDIENT CONTAINING OTHER THAN HYDROCARBON514/783, Plant extract or plant material of undetermined constitution514/938Oil-water type

Examiners

Primary: Friedman, Stanley J.

Attorney, Agent or Firm

International Class

A61K 9/107 (20060101)

Abstract

According to the method of the invention, the parenteral administration of water-insoluble pharmacologically active agents is enhanced wherein the agents are administered in the lipoid phase of a carrier emulsion comprising a microemulsion of a finely dispersed lipoid in an aqueous phase. The lipoid preferably has a mean particle size below 1 micron. This makes it possible to administer water-insoluble agents in high concentrations, and thus a lower dose, whereby a rapid onset of the pharmacological effect is accompanied by a markedly reduced incidence of injury to body tissues.

Other References

  • Remington's Pharmaceutical Sciences (1965), p. 288
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