U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Pharmaceutical compositions containing cardiac glycoside

Patent 4067960 Issued on January 10, 1978. Estimated Expiration Date: Icon_subject January 10, 1995. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2298122

2990333

3472931

Inventor

Assignee

Application

No. 05/746599 filed on 12/01/1976

US Classes:

424/455, Containing emulsions, dispersions, or solutions424/456, Gelatin514/26Cyclopentanohydrophenanthrene ring system

Examiners

Primary: Rosen, Sam

Attorney, Agent or Firm

International Class

A61K 9/48 (20060101)

Abstract

A cardiotonic dosage unit form comprises a soft gelatine capsule containing a liquid cardiotonic composition comprising (a) a cardiac glycoside, preferably digitoxin or digoxin; (b) dimethyl formamide or dimethyl acetamide; and (c) a liquid polyethylene glycol and also, optionally, (d) propylene glycol or glycerin.The weight ratio of dimethyl acetamide or dimethyl formamide to cardiac glyceride is preferably at least 5:1 and the polyethylene glycol preferably forms at least 75% by weight of the total composition contained in the gelatine capsule.

Other References

  • Chiou et al., Chem. Abst., vol. 75, (1971), pp. 143,955z
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