ApplicationNo. 05/746599 filed on 12/01/1976
US Classes:424/455, Containing emulsions, dispersions, or solutions424/456, Gelatin514/26Cyclopentanohydrophenanthrene ring system
ExaminersPrimary: Rosen, Sam
Attorney, Agent or Firm
International ClassA61K 9/48 (20060101)
AbstractA cardiotonic dosage unit form comprises a soft gelatine capsule containing a liquid cardiotonic composition comprising (a) a cardiac glycoside, preferably digitoxin or digoxin; (b) dimethyl formamide or dimethyl acetamide; and (c) a liquid polyethylene glycol and also, optionally, (d) propylene glycol or glycerin.The weight ratio of dimethyl acetamide or dimethyl formamide to cardiac glyceride is preferably at least 5:1 and the polyethylene glycol preferably forms at least 75% by weight of the total composition contained in the gelatine capsule.