Antiinflammatory azole derivatives
Patent 4051250 Issued on September 27, 1977. Estimated Expiration Date: 
September 27, 1994. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
September 27, 1994. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesInventorsAssigneeApplicationNo. 624447 filed on 10/21/1975US Classes:514/376, Chalcogen bonded directly to ring carbon of the oxazole ring514/369Chalcogen bonded directly to ring carbon of the thiazole ringExaminersPrimary: Schenkman, LeonardAttorney, Agent or FirmInternational ClassesA61K 031/42A61K 031/425 Foreign Application Priority Data1971-06-11 DTAbstractAzole derivatives of the formula ##STR1## wherein R1 is free or esterified carboxyl or other functionally modified carboxyl group, R2 and R3 each are aryl; A is Cn H2n in which n is an integer from 1 to 10, inclusive; and Z is O or S; and the physiologically acceptable salts thereof, possess, with good compatibility, excellent antiphlogistic activity and, in particular, influence favorably the chronic progressive diseases of the joints, e.g., arthritis. They can be prepared from compounds of the formula ##STR2## wherein X1 is a group convertible into the group --S--A--R1, and R2 and R3 have the values given above. | |
